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The aim of this SOP is to provide guidance on how to access the policy, procedure and documentation in the event of suspected cytotoxic extravasation.
Children receiving systemic anti-cancer therapy who sustain a suspected cytotoxic extravasation.
Medical and nursing staff involved in the care of the child receiving systemic anti-cancer therapy.
Extravasation is the inappropriate or accidental infiltration of SACT into the subcutaneous or subdermal tissues surrounding the administration site. The injuries range from less significant erythematous reactions to skin sloughing and necrosis. Whilst extravasation is possible with any intravenous injection it is only considered to be problematic with compounds knowns to have irritant or vesicant properties (see WOSCAN guidance – section 8). The onset of symptoms may occur immediately or several days to weeks after administration. If left undiagnosed or inappropriately treated, necrosis and functional loss of tissue and limb concerned may ensue.
As noted above, although it can occur with other drugs, this policy only covers cytotoxic drugs and the aim of this SOP is to provide guidance on how to access the policy, the procedure and the documentation in the event of suspected cytotoxic extravasation.
All personnel responsible for the administration of SACT must be appropriately trained and immediately access this SOP and the equipment listed in Section 4 on first suspicion of SACT extravasation and follow the pathway listed in Section 6. The process should be followed for any suspected extravasation. If, when reviewed by plastic surgery it is not defined as a true extravasation this should then be documented to complete the incident.
SUSPECTED EXTRAVASATION SHOULD BE TREATED AS A MEDICAL EMERGENCY
2.1 West of Scotland Cancer Network SACT Extravasation in Practice Policy, Guidance and Tools June 2015 [Intranet link]
2.2 Vascular Access Device Procedure & Practice Guideline 2019
2.3 Policy and Guidelines for the Safe Prescribing, Dispensing and Administration of Systemic Anti-Cancer Therapy (SACT) For Children, Teenagers and Young Adults Under The Care of the Haematology/Oncology Team RHC, Glasgow (Schiehallion Ward and Schiehallion Daycare Unit) (RHC-HAEM-ONC-014)
3.1 ALL medical, nursing and pharmacy staff involved in the care of the child receiving SACT
3.2 Nursing induction and orientation competency
3.3 Medical Induction
3.4 Extravasation training session
4.1 Extravasation kit and extravasation policy folder (located in treatment areas)
4.2 Hot/cold pack
4.3 Gloves
4.4 Visor
4.5 Armlets
4.6 Apron
NB: The nursing staff will obtain the extravasation kit and extravasation policy folder when SACT extravasation is suspected, however, it is the responsibility of the medical staff to ensure that all documentation is accurately completed and forwarded/filed as appropriate.
An appropriate system should be in place within each area to ensure these kits are within their expiry date. Replacement drugs should be ordered from Pharmacy well in advance of expiry dates. It is the responsibility of the nursing staff to check expiry date on the extravasation kit monthly
The expiry date of all stock drugs required in the event of an extravasation must be checked regularly. Replacement stock should be ordered from pharmacy services one month prior to the drug expiry date.
Prevention
Action
IF AN EXTRAVASATION IS SUSPECTED THE INFUSION should be stopped AND MEDICAL STAFF contacted IMMEDIATELY. ALL POTENTIAL EXTRAVASATIONS SHOULD BE TREATED AS A MEDICAL EMERGENCY.
STAFF SHOULD FOLLOW THE EXTRAVASATION FLOWCHART FOR GUIDANCE (POSTER DISPLAYED IN ALL SACT ADMINISTRATION AREAS – see Appendix 1).
Follow-up
Patient follow up should be arranged on discharge ie out-patient clinic or Schiehallion Day Care Unit. The patient’s progress should be closely monitored to allow further appropriate action to be taken if necessary. Observation and documentation of the injury should be on a daily basis initially and only extended when clinically indicated to a minimum weekly follow up on a planned basis.
All patients must have a six week review of the extravasation site (even if the site appears to have improved).
This SOP will be reviewed every two years
None.
WOSCAN SACT Extravasation in Practice - Policy, Guidance & Tools document. This is available via the West of Scotland Cancer Network intranet site.
Last reviewed: 01 November 2022
Next review: 30 November 2024
Author(s): W Taylor
Version: 6
Approved By: Schiehallion Clinical Governance Group
Document Id: HAEM-ONC-009