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NICE guidance from 2010 recommends that visual estimation of the severity of neonatal jaundice is no longer used as it is highly inaccurate. The absence of symptoms (i.e. “alert and feeding well”) is not a reliable indicator that treatment is not required either.
Instead whenever neonatal jaundice is seen, the serum bilirubin level should be estimated using transcutaneous bilirubinometry or measured with a blood sample.
This guideline describes the agreed process for the use of transcutaneous bilirubinometers in the community, and should be used in conjunction with the West of Scotland Neonatal MCN Jaundice guideline. Staff using this access should ensure that they have access to the appropriate gestation specific charts (see appendix), and should refer to them with all results.
Jaundice can develop at any time over the first few days of life. All possible opportunities should be used to look for jaundice over this time.
When looking for jaundice (visual inspection):
Assess for jaundice at every interaction with a newborn baby in the first days of life. Ensure adequate lighting. Document the absence or presence of jaundice whenever writing a clinical note. In the “colour” section of the daily check in Badgernet the presence or absence of jaundice should be noted each day.
Particular attention must be paid to the following groups:
Presence of these risk factors should be noted on admission to the ward and it should be ensured that they are regularly assessed for jaundice. NICE recommend that babies with the above factors associated with an increased likelihood of developing significant hyperbilirubinaemia receive an additional visual inspection by a healthcare professional during the first 48 hours of life.
All staff using a transcutaneous bilirubinometer should ensure that they have received adequate training in the use of the device that they have been provided with.
Except in the following circumstances where serum bilirubins should be measured:
Caution should also be used where there is known or suspected haemolysis (e.g. where there are maternal blood group antibodies of concern, a history of siblings with severe early haemolysis or the baby is DAT positive in keeping with haemolysis). In this group it may be prudent to use serum bilirubin measurements, at least initially. Any baby falling into this group (known or suspected haemolysis) should have their initial management in a hospital setting and a clear plan for follow up sampling etc made by the discharging paediatrician.
Babies over 14 days of age who are visibly jaundiced should follow guidance for prolonged jaundice.
Transcutaneous bilirubin levels of over 250micromol/l or within 25 micromol/l of the treatment line must have an SBR is checked to inform management.
A repeat measurement is recommended for those with a level within 50micromol/l of the treatment threshold, as follows:
For all levels, comparison with previous measurements where available is much more informative than looking at a single measurement.This should be borne in mind when using any of these thresholds. Where the rate of rise can be determined it should be used to plan future samples/referral to hospital rather than the action points below. This is particularly relevant on the flatter “plateau” phase of the charts (from 72 or 96 hours of age). If in doubt, please contact the neonatal medical staff/ANNPs for advice.
NICE recommend the following for infants >38 weeks gestation:
Process:
For all visibly jaundiced babies (greater than 24 hours, greater than 35 weeks and without previous phototherapy):
If previous measurements are available, decisions around the need for SBR sampling/referral to hospital will depend on whether the level is rising or falling, and the age of the child.
Transcutaneous billirubin actions, 38 weeks and over
Transcutaneous billirubin actions for 37 weeks gestation
Transcutaneous billirubin actions for 36 weeks gestation
Transcutaneous billirubin actions for 35 weeks gestation
Last reviewed: 03 June 2024
Next review: 01 June 2027
Author(s): Dr Allan Jackson – Neonatal Consultant PRM
Co-Author(s): Other Professionals Consulted: Veronica McArthur – Community Midwife PRM
Approved By: GGC Neonatal Guidelines Group