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Hyponatraemia is defined as plasma sodium <135mmol/L. There is an excess of water relative to sodium in the extracellular fluid compartment, due to an excess of water, a deficit of sodium or more commonly a combination of both. In order for hyponatraemia to develop ADH has to be present and there has to be a source of water. Acute hyponatraemia is arbitrarily defined as < 48 hours duration.
Last reviewed: 01 November 2016
Next review: 30 November 2019
Author(s): Anne Mcgettrick, Colin Begg, Graham Bell
Reviewer Name(s): RHC IV Fluid Group