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“MSSA is clearly a significant pathogen in CF patients. The aim of treatment is to prevent infection with, or eradicate MSSA infection from the respiratory tract” 1
“The European CF Consensus group evaluating early intervention in CF lung disease has recommended an initial 2–4 weeks of antistaphylococcal treatment with new S.aureus infection .If this eradication approach fails, they recommend a 1–3 month course of antibiotics.” 5
1. CF Trust Antibiotic Treatment for Cystic Fibrosis 2009
2. Brompton Paediatric CF Guidelines 2017 https://www.rbht.nhs.uk/our-services/paediatrics/paediatric-cystic-fibrosis-clinics/care-children-cystic-fibrosis-2017- [Revised prophylactic Azithromycin dose 2019 for inclusion in 2020 version]
3. Scottish Paediatric Cystic Fibrosis Managed Clinical Network Prescribing Guidelines 2015
4. The Leeds Method of Management. April, 2008.
5. Goss C, Muhlebach M. Review: Staphylococcus aureus and MRSA in cystic fibrosis. Journal of Cystic Fibrosis 10 (2011) 298–306
Last reviewed: 25 May 2022
Next review: 24 May 2023
Author(s): Louise Thomson, Anne Devenny
Version: 2
Approved By: Paediatric Drugs & Therapeutics Committee
Document Id: 703