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Use of Proton Pump Inhibitors (PPIs) in Neonates and Paediatrics.
The aim of this guideline is to standardise prescribing practice of PPIs whilst ensuring patients are given appropriate and effective treatments.
This guideline covers the use of PPIs in neonates and paediatrics, across primary and secondary care, within NHS Greater Glasgow and Clyde. It is intended for use by all health professionals involved in the care of these patients.
PPIs are indicated for use in patients for:
The need for ongoing treatment should be reviewed regularly and is particularly important for infant GORD.
Licensed suspensions of oral omeprazole are available, however there are limitations to the use of these products (see further advice section in attached document), and these products are not currently recommended for use for paediatric patients in NHSGGC.
Within general paediatrics, orodispersible tablet and capsule formulations of PPIs have been used successfully with little need for alternatives (see tables in attached document for further advice).
Last reviewed: 12 May 2021
Next review: 01 April 2023
Author(s): Natalie Donald
Approved By: Medicines Utilisation Subcommittee of ADTC