Nitric Oxide administration in MRI
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Nitric Oxide administration in MRI

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Objectives

Nitric oxide delivery systems cannot be taken into the MRI scanner room, this document explains the configuration required for scanning a patient receiving inhaled NO.

Scope

This document applies only to patients who are intubated & ventilated receiving inhaled Nitric Oxide (NO) in PICU or NICU in RHC. NO can only be delivered in the 1st floor MRI scanner 

Audience

All NICU, PICU and anaesthetic staff within RHC Glasgow 

Administration of nitric oxide within the MRI scanner will be an uncommon procedure but cases will occasionally arise. Experience with patients in the past is that the delivery systems are awkward and the ergonomics have been poor in terms or equipment arrangement at the entrance to the scanning room. Alterations have been made in order that we can now use standard administration equipment and configure this in a way that will closely resemble a routine anaesthetic administration in MRI 

Before the scan

Planning of potential cases MUST involve the anaesthetic department. It is possible to set up the entire breathing system in with NO at the required concentration running through the breathing system prior to collecting the patient from PICU / NICU. This will allow an easy transfer at the scanning room door with a simple switch of the patient breathing system connection. 

Set up

The Nitric Delivery system can sit in the control room next to the monitor.

 

The Nitric delivery system should go through the lower wave guide (pass the tubes from the scanning room backwards towards the machine – they don’t fit the other way round). Blue plugs are for medical equipment, plug the nitric delivery system in here.

The nitric delivery & monitoring tubing are connected into the circle system as we would do in theatre i.e. delivery attachment directly onto the inspiratory limb of the circle and the monitoring  / sampling line further up the inspiratory limb.  Different types of soda lime have different effects in reducing both NO and NO2 within the circle system, whilst most of these are minor we do not recommend using low flow anaesthesia. [1]

We have put the sampling line in-between 2 tube extensions in this example.

2 or 3 sets of tubing extensions are required (depending of the position of your patient in the scanner) – work out the maximum distance when setting up the kit prior to calibration of the NO delivery system.

The gas tubes are long enough to move the anaesthetic machine all the way to sit on the left of the door at the internal side of the wave guides. Suction and scavenging have not been connected in this image – use the extension tubes hanging on the rear of the anaesthetic machine.

Once the system is assembled, put a test lung on the patient end, set up the ventilator to your patient’s requirements & run the calibration of the Nitric delivery system. You will need a flow of 10lpm of O2 through the circle system for this.

There is  usually no need to set up a t-piece system for bagging. If the patient requires manual ventilation e.g. for ETT suction then this can be accomplished by switching to the bag on the circle system.

If a t-piece is required, it can be set up in advance & passed through the wave guide, but the user will be in scan and the selection of breathing system is in the control room, so it requires additional personnel & potentially awkward communication so it is recommended that the manual ventilation bag on the circle is used whenever possible.

Useful contacts

MRI 1st Floor (main paediatric scanner) radiology Ex 84270  0141 452 4270

If you require further advice please contact Dr Graham Bell, graham.bell@ggc.scot.nhs.uk or mobile via switchboard

References

PICKETT, A.H. et al. The role of soda lime during administration of inhaled nitric oxide, British Journal of Anaesthesia, 72(6):683-685.

Editorial Information

Last reviewed: 12 July 2023

Next review: 31 July 2026

Author(s): Dr Graham Bell, Consultant Anaesthetist; Dr Pauline Hall-Barrientos, Hospital Physics; Ms Marie Pirie, Superintendent Radiographer; Mr Kevin Jerome, Senior ODP

Approved By: Paediatric Guidelines Group

Document Id: 1095